Infertility can result from various factors affecting both men and women. Here’s an overview of the common causes:
Causes of Infertility in Women

- Ovulation Disorders:
- Polycystic Ovary Syndrome (PCOS): A hormonal disorder causing irregular ovulation.
- Hypothalamic Dysfunction: Issues with the hormones produced by the hypothalamus affecting ovulation.
- Premature Ovarian Insufficiency: Early decline in ovarian function, often due to genetics or autoimmune issues.
- Hyperprolactinemia: High levels of prolactin can interfere with ovulation.
- Uterine or Cervical Abnormalities:
- Uterine Fibroids: Non-cancerous growths in the uterus.
- Polyps: Growths on the inner wall of the uterus.
- Cervical Stenosis: Narrowing of the cervix.
- Uterine Malformations: Structural abnormalities in the uterus.
- Fallopian Tube Damage or Blockage:
- Pelvic Inflammatory Disease (PID): Often caused by sexually transmitted infections.
- Previous Surgery: Procedures like tubal ligation reversal or abdominal surgeries.
- Ectopic Pregnancy: A pregnancy outside the uterus, often in the fallopian tube.
- Endometriosis:
- Growth of endometrial tissue outside the uterus, causing blockages and affecting ovulation.
- Primary Ovarian Insufficiency:
- Early menopause or significant decline in the number of eggs produced.
- Age:
- Decline in fertility after age 35 due to reduced quantity and quality of eggs.
- Other Medical Conditions:
- Thyroid Disorders: Both hyperthyroidism and hypothyroidism.
- Diabetes: Poorly controlled blood sugar can impact fertility.
Causes of Infertility in Men

- Sperm Disorders:
- Low Sperm Count: Insufficient sperm production.
- Poor Sperm Motility: Sperm that can’t swim well.
- Abnormal Sperm Morphology: Sperm with abnormal shape.
- Azoospermia: Absence of sperm in the semen.
- Hormonal Imbalances:
- Issues with hormones that control sperm production such as testosterone and other hormones.
- Testicular Problems:
- Varicocele: Enlarged veins in the scrotum affecting sperm production.
- Infections: Such as orchitis or sexually transmitted infections.
- Ejaculation Disorders:
- Retrograde Ejaculation: Semen enters the bladder instead of exiting through the penis.
- Premature Ejaculation: Rapid ejaculation can sometimes affect conception.
- Genetic Factors:
- Klinefelter Syndrome: Presence of an extra X chromosome.
- Y Chromosome Microdeletions: Missing genetic material on the Y chromosome.
- Environmental and Lifestyle Factors:
- Exposure to Toxins: Such as pesticides, radiation, and heavy metals.
- Substance Abuse: Alcohol, tobacco, and drugs.
- Obesity: Can affect hormone levels and sperm quality.
- Heat Exposure: Prolonged exposure to high temperatures, such as in hot tubs or saunas.
Shared Factors Affecting Both Genders

- Lifestyle Factors:
- Stress: Chronic stress can impact hormonal balance.
- Diet: Poor nutrition can affect overall reproductive health.
- Exercise: Both excessive exercise and lack of physical activity can impact fertility.
- Medical Treatments:
- Cancer Treatments: Chemotherapy and radiation can impair fertility.
- Medications: Certain drugs can affect reproductive health.
- Sexually Transmitted Infections (STIs):
- Can cause damage to reproductive organs in both men and women.
Understanding the specific cause of infertility often requires a thorough medical evaluation, including medical history, physical examination, and specialized tests. Treatment options vary widely depending on the underlying cause and may include medication, surgery, lifestyle changes, or assisted reproductive technologies such as in vitro fertilization (IVF).
